Cilastatin

• Catalog Number: orb1305299
• Category: Small Molecules
• Description: Cilastatin
• CAS Number: 82009-34-5
• Purity: 99.71%
• MW: 358.45
• SMILES: C(N/C(=C\CCCCSC[C@@H](C(O)=O)N)/C(O)=O)(=O)[C@@H]1C(C)(C)C1
• Formula: C₁₆H₂₆N₂O₅S
• Biological Activity: Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.