CIDD-8633

SKU: orb3135805

Description

CIDD-8633 is a potent inhibitor of DDR2 with an IC50 of 6.105 μM. It significantly suppresses the proliferation of MIA-PaCa-2 and AsPC-1 cells, with IC25 values of 4.0 and 5.5 μM, respectively. Additionally, CIDD-8633 hinders cell migration, arrests the cell cycle, induces apoptosis (apoptosis), and substantially reduces the growth of pancreatic ductal adenocarcinoma (PDAC) tumors. This compound is applicable in pancreatic cancer research, including studies on PDAC.

Research Area

Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 1428356-95-9
• MW: 445.4771
• Formula: C₂₂H₂₃N₉O₂
• SMILES: CCNC1=NC(NC2=CC=C(NC(=O)COC3=CC=C(N=N3)N3C=CC=N3)C=C2)=CC(C)=N1
• Target: Caspase,Interleukin,Discoidin Domain Receptor (DDR),Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase,Interleukin,Discoidin Domain Receptor (DDR),Apoptosis