CID5721353

SKU: orb1303535

Description

CID5721353 is a potent and selective small molecule BCL6 inhibitor that disrupts BCL6-corepressor interactions by binding the BTB domain groove. It is a valuable research tool for studying BCL6 function in lymphomagenesis and immune regulation, with demonstrated activity in both in vitro biochemical assays and in vivo disease models.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 301356-95-6
• MW: 457.28
• Purity: 99.20% (May vary between batches)
• Formula: C₁₅H₉BrN₂O₆S₂
• SMILES: OC(=O)CC(N1C(=S)S\C(C1=O)=C1\C(=O)Nc2ccc(Br)cc12)C(O)=O
• Target: Apoptosis,Bcl-2 Family,Bcl-6
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.37 mM);DMSO:60 mg/mL (131.21 mM)

Bioactivity

• Target IC50:
  Bcl-6:212 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CID 5721353, CID5721353, CID-5721353, Bcl-2 Family, Bcl-6, BCL6 inhibitor, Apoptosis, Inhibitor, inhibit

Compound Identifiers

PubChem CID

3800971