CIA-1 (Free base)

SKU: orb1819129

Description

CIA-1 (Free base) is a small molecule inhibitor of the nuclear receptor COUP-TFII, demonstrating in vitro activity with IC50 values of 1.2-7.6 μM in prostate cancer cells. It has also shown efficacy in inhibiting tumor growth in mouse xenograft models, supporting its use in oncology research for studying hormone-related cancers.

Research Area

Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 452087-38-6
• MW: 329.42
• Purity: 99.00%
• Formula: C₁₇H₁₉N₃O₂S
• SMILES: N(CCC1=CC(OC)=C(OC)C=C1)C2=C3C(SC(C)=C3)=NC=N2
• Target: Orphan Receptor,Others,Gamma-secretase
• Solubility: DMSO:60 mg/mL (182.14 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COUP-TFII, CIA 1, CIA1, CIA-1, CIA-1(Free base), CIA-1(Free base), Gamma-secretase, Gammasecretase

Compound Identifiers

PubChem CID

2229408