CHS-111

SKU: orb1700864

Description

CHS-111 is a benzyl indazole inhibitor of phospholipase D1 (PLD1) activity, disrupting its interaction with Arf6 and RhoA. It suppresses fMLP-stimulated superoxide generation and RhoA membrane recruitment, making it a useful research tool for studying neutrophil signaling and inflammation in cellular models.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 886755-63-1
• MW: 314.38
• Formula: C₂₁H₁₈N₂O
• SMILES: C(N1C(=C2C(=N1)C=CC=C2)C3=CC=C(CO)C=C3)C4=CC=CC=C4
• Target: Reactive Oxygen Species,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

23120781