Choline bitartrate

SKU: orb1300450

Description

Choline bitartrate, a dietary source of the essential nutrient choline, is critical for hepatic and renal health and serves as a precursor for the neurotransmitter acetylcholine. It is widely used in neuroscience and nutrition research to study cholinergic signaling, liver metabolism, and cellular membrane integrity in both in vitro and in vivo experimental models.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 87-67-2
• MW: 253.25
• Purity: 99.79% (May vary between batches)
• Formula: C₅H₁₄NO·C₄H₅O₆
• SMILES: C[N+](C)(C)CCO.OC(C(O)C([O-])=O)C(O)=O
• Target: Endogenous Metabolite,AChR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.9 mM);DMSO:11 mg/mL (43.44 mM)

Bioactivity

• In Vivo:
  Choline is critical for normal brain development. Choline deficiency has other health consequences—it is associated with liver and muscle damage and with an exaggerated plasma homocysteine rise after a methionine load. Elevated plasma homocysteine is an independent risk factor for cardiovascular disease and stroke in humans. But choline bitartrate does not improve remembrance of spatial locations, declarative items, and verbal words.
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• In Vitro:
  Choline is an essential nutrient needed for the structural integrity and signaling functions of cell membranes; for normal cholinergic neurotransmission; for normal muscle function; for lipid transport from liver; and it is the major source of methyl groups in the diet.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Choline bitartrate, 2-hydroxyethyl(trimethyl)azanium, 2,3,4-trihydroxy-4-oxobutanoate, Inhibitor, mAChR, Muscarinic acetylcholine receptor, inhibit

Compound Identifiers

PubChem CID

10198924