Cholic acid sodium hydrate

SKU: orb1982004

Description

Cholic acid sodium hydrate is a primary bile acid that facilitates fat absorption and cholesterol excretion. It is widely used in research on lipid metabolism, digestive physiology, and as a critical reagent for in vitro studies of bile acid transporters and nuclear receptor signaling (e.g., FXR).

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 206986-87-0
• MW: 448.57
• Formula: C₂₄H₄₀O₅.xH₂O.Na
• SMILES: O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H].[Na].O
• Target: Others

Bioactivity

• In Vivo:
  Cholic acid sodium hydrate (1% cholic acid supplemented diet, oral, 14 days) may reduce SHP (small heterodimer partner) protein expression via upregulation of miR142-3p.
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• In Vitro:
  Cholic acid sodium hydrate (1 mg/mL, 30 minutes) competitively binds to Na+/taurocholate cotransporting polypeptide (NTCP) on HepG2 cells.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

23679061