Chikusetsusaponin IVa

SKU: orb1303644

Description

Chikusetsusaponin IVa (Calenduloside F) is a novel AMPK activator that stimulates insulin secretion in βTC3 cells via GPR4-mediated calcium and PKC signaling. This activity suggests its potential as a research tool for investigating type 2 diabetes mellitus (T2DM) pathways in cellular models.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 51415-02-2
• MW: 794.97
• Purity: 99.64% (May vary between batches)
• Formula: C₄₂H₆₆O₁₄
• SMILES: CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
• Target: Nrf2,AMPK
• Solubility: DMSO:60 mg/mL (75.47 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.52 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, AMPK, Chikusetsusaponin IVa, Calenduloside F

Compound Identifiers

PubChem CID

13909684