Chicanine

SKU: orb1684707

Description

Chicanine is a natural lignan compound with demonstrated anti-inflammatory activity. It functions by inhibiting LPS-induced phosphorylation of key signaling proteins p38 MAPK, ERK1/2, and IκB-α in macrophages. This mechanism supports its research use in studying inflammatory pathways in both cellular and animal models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 78919-28-5
• MW: 342.39
• Formula: C₂₀H₂₂O₅
• SMILES: C[C@H]1[C@@](O[C@]([C@H]1C)(C2=CC(OC)=C(O)C=C2)[H])(C=3C=C4C(=CC3)OCO4)[H]
• Target: Prostaglandin Receptor,IκB/IKK,NF-κB,ERK,p38 MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11078392