CH5138303

SKU: orb1685663

Description

CH5138303 is a potent, orally bioavailable small molecule inhibitor of Hsp90, exhibiting a dissociation constant (Kd) of 0.48 nM. It is utilized in cancer research to study oncogenic client protein degradation and has demonstrated antitumor efficacy in both cellular assays and in vivo xenograft models.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 959763-06-5
• MW: 415.9
• Formula: C₁₉H₁₈ClN₅O₂S
• SMILES: ClC1=C(C2=C3C(=C1)COCC3=CC=C2)C=4N=C(SCCCC(N)=O)N=C(N)N4
• Target: HSP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25066238