CH-5132799 Mesylate

SKU: orb2815406

Description

CH5132799 (PA-799) is a potent and orally active PI3Kα inhibitor (IC₅₀=0.014 µM) with specific activity against class I PI3K and mutant isoforms. It demonstrates robust antiproliferative effects in vitro and induces significant tumor regression in vivo, particularly in models with PIK3CA mutations or activated PI3K pathway signaling.

Key Properties

• CAS Number: 2242053-82-1
• MW: 473.53
• Formula: C₁₆H₂₃N₇O₆S₂
• SMILES: O=S(=O)(O)C.O=S(=O)(N1C2=NC(=NC(C3=CN=C(N=C3)N)=C2CC1)N4CCOCC4)C

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137331887