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CGS 27023A

SKU: orb1304171

Description

CGS 27023A is a potent, orally bioavailable small molecule inhibitor of stromelysin (MMP-3). It is utilized in research to investigate matrix metalloproteinase function in models of arthritis, cancer, and tissue remodeling in both cellular and animal studies.

Research Area

Protein Biochemistry

Images & Validation

Key Properties

CAS Number161314-82-5
MW429.92
Purity99.08% (May vary between batches)
FormulaC18H24ClN3O5S
SMILESC(=O)([C@@H](C(C)C)N(Cc1cnccc1)S(=O)(=O)c1ccc(cc1)OC)NO.Cl
TargetMMP
SolubilityDMSO:4.3 mg/mL (10 mM)

Bioactivity

Target IC50
MMP9:8 nM (Ki)|collagenases 1:33 nM (Ki)|MMP3:43 nM (Ki)|MMP2:20 nM (Ki)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CGS 27023A, MMP

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 90.00
2 mg
$ 100.00
5 mg
$ 130.00
10 mg
$ 160.00
25 mg
$ 330.00