Cart summary

You have no items in your shopping cart.

CGS 27023A

SKU: orb1304171

Description

CGS 27023A is a potent, orally bioavailable small molecule inhibitor of stromelysin (MMP-3). It is utilized in research to investigate matrix metalloproteinase function in models of arthritis, cancer, and tissue remodeling in both cellular and animal studies.

Research Area

Protein Biochemistry

Images & Validation

Key Properties

CAS Number161314-82-5
MW429.92
Purity99.08%
FormulaC18H24ClN3O5S
SMILESC(=O)([C@@H](C(C)C)N(Cc1cnccc1)S(=O)(=O)c1ccc(cc1)OC)NO.Cl
TargetMMP
SolubilityDMSO:4.3 mg/mL (10 mM)

Bioactivity

Target IC50
MMP9:8 nM (Ki)|collagenases 1:33 nM (Ki)|MMP3:43 nM (Ki)|MMP2:20 nM (Ki)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CGS 27023A, MMP

Similar Products

  • CGS-27023A HCl [orb1739095]

    161314-70-1

    393.46

    C18H23N3O5S

    50 mg, 100 mg, 25 mg
  • CGS 27023A [orb1223264]

    >98% (HPLC)

    161314-82-5

    429.9

    C18H24ClN3O5S

    1 g, 500 mg, 200 mg, 100 mg, 2 mg, 10 mg, 25 mg, 5 mg, 50 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download
Manual
Product Manual
Download
MSDS
Safety Data Sheet
Download

Request a Document

Protocol Information

CGS 27023A (orb1304171)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 90.00
2 mg
$ 100.00
5 mg
$ 130.00
10 mg
$ 160.00
25 mg
$ 330.00
50 mg
$ 470.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry