β-CGRP, human acetate

SKU: orb1296355

Description

β-CGRP, human acetate

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• MW: 3853.46
• Purity: 99.35% (May vary between batches)
• Formula: C₁₆₄H₂₇₁N₅₁O₅₀S₃
• Target: CGRP Receptor

Bioactivity

• Target IC50:
  CRLR/RAMP2:300 nM |CRLR/RAMP1:1 nM
• In Vitro:
  β-CGRP, human acts via a complex of the CRLR and RAMP, with IC50s of 1 nM in both SK-N-MC and Swiss 3T3 cells express CRLR and RAMP1, and 300 nM and 130 nM in HEK293T and NG108-15 cells expressing CRLR and RAMP2 . CGRP is a potent vasodilator and also exhibits pro- and -anti-inflammatory activity .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

b-CGRP, human Acetate, 101462-82-2 free, CRLR/RAMP1, CRLR/RAMP1, cell assay, CRLR/RAMP2, CRLR/RAMP2, cell assay, CGRP Receptor, CGRP-II (Human), CGRP-II (Human) (acetate), CGRPReceptor, beta-CGRP, human Acetate, Human β-CGRP acetate, Human β-CGRP Acetate, Human beta-CGRP Acetate, Human b-CGRP Acetate, β CGRP, human acetate, βCGRP, human acetate, β-CGRP, human Acetate, β-CGRP, human acetate (101462-82-2 free)

Quick Database Links

Gene Symbol

CGRP Receptor