CGP-74514

SKU: orb3029072

Description

CGP-74514 (Compound 13) is a highly selective cyclin-dependent kinase 1 (CDK1) inhibitor (IC50=25 nM). This compound inhibits CDK1/cyclin B complex activity, resulting in G2/M phase cell cycle arrest and induction of tumor cell apoptosis, demonstrating promising applications in bladder cancer research.

Research Area

Cell Biology

Key Properties

• CAS Number: 190653-73-7
• MW: 385.89
• Purity: 98.54% (May vary between batches)
• Formula: C₁₉H₂₄ClN₇
• SMILES: N(C1=C2C(N(CC)C=N2)=NC(N[C@@H]3[C@H](N)CCCC3)=N1)C4=CC(Cl)=CC=C4
• Target: Apoptosis,CDK

Bioactivity

• Target IC50:
  CDK1-CyclinB1:25 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CGP74514

Quick Database Links

Gene Symbol

Apoptosis,CDK