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CGP 57380

SKU: orb1224809

Description

A cell-permeable, specific MNK1 inhibitor with IC50 of 2.2 uM; has no inhibitory activity on p38, JNK1, ERK1/2, etc.; inhibits phosphorylation of eIF4E in cellular assays with IC50 of 3 uM.

Images & Validation

Key Properties

CAS Number522629-08-9
MW244.2278
Purity>98% (HPLC)
FormulaC11H9FN6
SMILESNC1=C2C(NN=C2NC3=CC=C(F)C=C3)=NC=N1
TargetMNK
SolubilityDMSO: ≥ 43 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CGP57380 | CGP-57380

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Protocol Information

Available Sizes

Select a size below

500 mg
2 mg
$ 110.00
5 mg
$ 160.00
10 mg
$ 240.00
25 mg
$ 440.00
50 mg
$ 720.00
100 mg
$ 1,030.00
200 mg
$ 1,430.00