CGP 55845

SKU: orb1738949

Description

CGP 55845 is a potent and selective GABAB receptor antagonist with a pKi of 8.35, effectively blocking agonist binding. It inhibits the release of GABA and glutamate, demonstrated by pEC50 values of 8.08 and 7.85, respectively. This compound is widely used in neuroscience research to study synaptic transmission and neurotransmitter release in both in vitro and in vivo models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 150175-54-5
• MW: 402.25
• Formula: C₁₈H₂₂Cl₂NO₃P
• SMILES: [C@H](NC[C@@H](CP(CC1=CC=CC=C1)(=O)O)O)(C)C2=CC(Cl)=C(Cl)C=C2
• Target: GABA Receptor,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5311042