cGMP Dependent Kinase Inhibitor Peptide acetate

SKU: orb3180299

Description

cGMP Dependent Kinase Inhibitor Peptide acetate is a highly selective, ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG/cGKI). cGMP Dependent Kinase Inhibitor Peptide acetate is a synthetically produced peptide with a Ki value of 86 μM. cGMP Dependent Kinase Inhibitor Peptide acetate inhibits PKG-dependent myosin light chain phosphorylation in vascular smooth muscle cells, blocking vasodilatory signaling, and is used in cardiovascular disease research. cGMP Dependent Kinase Inhibitor Peptide acetate also inhibits PfPKG in Plasmodium and Toxoplasma, and is used in antiparasitic research.

Research Area

Signal Transduction

Key Properties

• MW: 1003.16
• Purity: 99.92% (May vary between batches)
• Formula: C₄₀H₇₈N₁₈O₁₂
• SMILES: CC(O)=O.C[C@H](NC(=O)[C@H](CCC\N=C(\N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC\N=C(\N)N)C(=O)N[C@@H](CCC\N=C(\N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(O)=O
• Target: PKA

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PKA