CGK012

SKU: orb2566618

Description

CKG012 is a small molecule Wnt/β-catenin pathway inhibitor that suppresses HMGB1 release and β-catenin-driven transcription. It has demonstrated attenuating effects in research models of sepsis (e.g., CLP-induced) and multiple myeloma, showing potential for both in vitro and in vivo experimental applications.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2044497-76-7
• MW: 357.40
• Formula: C₂₀H₂₃NO₅
• SMILES: O(C(NC1CCCC1)=O)[C@H]2CC=3C(=CC4=C(C3)C=CC(=O)O4)OC2(C)C
• Target: Wnt/beta-catenin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162532632