cGAS-IN-2

SKU: orb2566641

Description

cGAS-IN-2 (compound 109) is a highly potent and selective inhibitor of human cGAS, demonstrating an IC50 of 15.12 nM. This tool compound is widely used in biochemical and cellular assays to investigate the cGAS-STING signaling pathway in autoimmune diseases, cancer immunology, and viral infection research.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Key Properties

• CAS Number: 2765273-11-6
• MW: 341.23
• Formula: C₁₆H₁₈Cl₂N₂O₂
• SMILES: C[C@H]1C=2C=3C(NC2C[C@@H](C)N1C(COC)=O)=C(Cl)C(Cl)=CC3
• Target: cGAS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171034419