CG-3-246

SKU: orb2945816

Description

CG-3-246 is a potent small molecule dual inhibitor of FLT3 (Kd=63 nM) and BCL-2 (Kd=4.25 nM). It is a valuable research tool for studying acute myeloid leukemia (AML), demonstrating activity in both cellular assays and in vivo models of the disease.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3107307-79-6
• MW: 1265.87
• Formula: C₆₄H₇₃ClN₁₄O₁₀S
• SMILES: CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCN(CC3)C(=O)CNC4=C(C=C(C=C4)S(=O)(=O)NC(=O)C5=C(C=C(C=C5)N6CCN(CC6)CC7=C(CC(CC7)(C)C)C8=CC=C(C=C8)Cl)OC9=CN=C1C(=C9)C=CN1)[N+](=O)[O-])OC)NC1CCOCC1
• Target: Bcl-2 Family,FLT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677080