CG-1521

SKU: orb3211535

Description

CG-1521 is a histone deacetylase (HDAC) inhibitor that stabilizes Ac-Lys373P53, increases P21 levels, and promotes the degradation of HDAC2. It suppresses proliferation, induces cell cycle arrest, and triggers apoptosis. Additionally, CG-1521 facilitates the translocation of Bax to the mitochondria and its cleavage. It also downregulates the expression of KIF4, Aurora B, Nek2 proteins, and DNA synthesis. CG-1521 is applicable in research on prostate cancer and inflammatory breast cancer.

Key Properties

• CAS Number: 674767-29-4
• MW: 215.25
• Formula: C₁₃H₁₃NO₂
• SMILES: C(=C/C=C/C=C/C(NO)=O)\C1=CC=CC=C1
• Target: DNA/RNA Synthesis,HDAC,MAPK,MDM-2/p53,Aurora Kinase,Bcl-2 Family,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA/RNA Synthesis,HDAC,MAPK,MDM-2/p53,Aurora Kinase,Bcl-2 Family,Apoptosis