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CFI-400945

SKU: orb1218916

Description

CFI-400945 is an potent, selective and orally active inhibitor of polo-like kinase 4(PLK4; Ki value of 0.26 nM).

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number1338806-73-7
MW534.65
Purity>98% (HPLC)
FormulaC33H34N4O3
SMILESC[C@@H]1CN(C[C@@H](O1)C)CC2=CC=C(C=C2)/C=C/C3=NNC4=C3C=CC(=C4)[C@@H]5C[C@]56C7=C(C=CC(=C7)OC)NC6=O
TargetPLK
SolubilityDMSO:100 mg/mL (187.04 mM;warmed with 50oC water bath);Ethanol:100 mg/mL (187.04 mM);Water:Insoluble

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Protocol Information

Available Sizes

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200 mg
500 mg
2 mg
$ 150.00
5 mg
$ 240.00
10 mg
$ 370.00
25 mg
$ 690.00
50 mg
$ 1,010.00
100 mg
$ 1,430.00