Cetagliptin

SKU: orb2814620

Description

Cetagliptin is a DPP-4 and CYP2D6 inhibitor (IC50 = 6 µM) that acts as a P-glycoprotein substrate. It is used in diabetes research to study mechanisms of glycemic control by preserving incretin hormones like GLP-1 in both in vitro and in vivo models.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 2243737-33-7
• MW: 518.35
• Formula: C₁₈H₂₁F₆N₄O₅P
• SMILES: P(=O)(O)(O)O.C(F)(F)(F)C=1N2C([C@@H](C)N(C(C[C@@H](CC3=C(F)C=C(F)C(F)=C3)N)=O)CC2)=CN1
• Target: Cytochromes P450,P-gp,Proteasome

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677438