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Ceritinib mesylate

SKU: orb3210975

Description

Ceritinib (LDK378) mesylate is a selective and orally bioavailable ALK tyrosine kinase inhibitor that binds to ATP, with an IC50 value of 200 picomoles. Additionally, Ceritinib mesylate can inhibit IGF-1R, InsR, and STK22D, with IC50 values of 8, 7, and 23 nanomoles, respectively. It exhibits significant antitumor activity.

Images & Validation

Key Properties

CAS Number2055376-74-2
MW750.35
FormulaC30H44ClN5O9S3
SMILESO=S(O)(C)=O.O=S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCNCC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(C(C)C)=O.O=S(O)(C)=O
TargetALK,IGF-1R

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information