Ceralasertib formate

SKU: orb1700891

Description

Ceralasertib is a selective, orally bioavailable ATR kinase inhibitor that blocks CHK1 phosphorylation, disrupting DNA damage repair and checkpoint signaling to induce apoptosis. It is widely used in preclinical oncology research, both in vitro and in vivo, to investigate synthetic lethality and combination therapies with DNA-damaging agents.

Research Area

Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 1352280-98-8
• MW: 458.54
• Formula: C₂₁H₂₆N₆O₄S
• SMILES: OC=O.C[C@@H]1COCCN1c1cc(nc(n1)-c1ccnc2[nH]ccc12)C1(CC1)[S@](C)(=N)=O
• Target: Others,ATM/ATR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

154701782