Cephalosporin C zinc salt

SKU: orb1220491

Description

Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM) and this inhibition was largely attributable to the presence of zinc.

Key Properties

• CAS Number: 59143-60-1
• MW: 478.78
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₉N₃O₈SZn
• SMILES: [Zn++].[H][C@@]12SCC(CC(C)=O)=C(N1C(=O)[C@H]2NC(=O)CCC[C@@H](N)C([O-])=O)C([O-])=O
• Target: SAMHD1
• Solubility: DMSO:6 mg/mL (12.53 mM)

Bioactivity

• In Vitro:
  Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 ± 0.1 μM, 200-fold more potent than Na+ salt form of Cephalosporin C (ICC50CC-Na = 213 ± 30 μM).

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

SAMHD1