CEP-28122 mesylate salt (1022958-60-6 free base)

SKU: orb1309847

Description

CEP-28122 mesylate salt, derived from the free base (CAS 1022958-60-6), is a potent and orally bioavailable inhibitor of ALK with high selectivity, demonstrating an IC50 of 1.9 nM in enzymatic assays. This compound is a valuable research tool for investigating ALK-driven pathologies, such as non-small cell lung cancer, in both cellular and animal models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• Target: ALK
• Molecular Weight: 635.17
• Purity: 99.79% (May vary between batches)
• Formula: C₂₉H₃₉ClN₆O₆S
• SMILES: COC1=C(C=CC2=C1CC[C@H](CC2)N3CCOCC3)NC4=NC=C(C(N[C@@H]5[C@@H]6C[C@H]([C@@H]5C(N)=O)C=C6)=N4)Cl.CS(=O)(O)=O

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ALK, 1022958-60-6, 1022958-60-6 free base, CEP 28122 mesylate salt (1022958 60 6 free base), CEP 28122 Mesylate, CEP28122 Mesylate, CEP-28122 Mesylate, CEP-28122 mesylate salt, CEP28122 mesylate salt (1022958606 free base)

Compound Identifiers

PubChem CID

91885507