CDN-3

SKU: orb3180285

Description

CDN-3 (Compound 10) is a cyclic dinucleotide derivative. It can stimulate THP-1 cells to secrete IFN-β, activate the IRF-3 and NF-κB pathways, and induce the production of type I interferons and pro-inflammatory factors such as IL-6 and TNF-α. Additionally, CDN-3 can inhibit the proliferation of CT26 cancer cells and is useful for colon cancer research.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 2768839-23-0
• MW: 742.97
• Formula: C₂₀H₂₂ClFN₁₀O₁₀P₂S₂
• SMILES: O[C@H]1[C@@]2([C@H](N3C4=C(N=C3)C(=O)N=C(N)N4)OC1(COP(=O)(S)O[C@@]5([C@@](COP(=O)(S)O2)(O[C@H]([C@H]5F)N6C=7C(N=C6)=C(N)N=C(Cl)N7)[H])[H])[H])[H]
• Target: IFNAR,Interleukin,TNF,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

IFNAR,Interleukin,TNF,NF-κB