CDKI-83

SKU: orb1738193

Description

CDKI-83 is a potent and selective CDK9 inhibitor with anti-proliferative activity (GI50 <1 μM) in tumor cell lines. It induces apoptosis in A2780 ovarian cancer cells, evidenced by caspase-3 activation and sub-G1 accumulation, suggesting potential as an anticancer agent through combined CDK9/CDK1 inhibition.

Research Area

Cell Biology

Key Properties

• CAS Number: 1189558-88-0
• MW: 485.58
• Formula: C₂₁H₂₃N₇O₃S₂
• SMILES: C(#N)C=1C(=NC(NC2=CC(S(=O)(=O)N3CCOCC3)=C(C)C=C2)=NC1)C=4SC(NC)=NC4C
• Target: Others,Apoptosis,CDK,Bcl-2 Family

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44224280