CDK9/PARP-IN-1

SKU: orb2944368

Description

CDK9/PARP-IN-1 (compound 37) is a dual inhibitor of CDK9 and PARP1 with IC50 values of 118 nM and 107 nM, respectively. It shows broad-spectrum anti-proliferative activity in cancer cell lines and is a useful chemical probe for studying DNA damage response and transcription in oncology research.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 3032818-67-7
• MW: 688.725
• Formula: C₃₈H₃₄F₂N₈O₃
• SMILES: O=C1NN=C(C=2C=CC=CC12)CC3=CC=C(F)C(=C3)C(=O)N4CCN(CC=5C=CN=C(C5)NC6=NC=NC(=C6)C=7C=CC(F)=CC7OCC)CC4
• Target: PARP,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

173640859