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CDK9-IN-36

SKU: orb2944572

Description

CDK9-IN-36 (Compound T7) is a potent, selective, and metabolically stable CDK9 inhibitor with an IC50 value of 1.2 nM. It effectively suppresses the proliferation of Osimertinib-resistant NSCLC cells by downregulating Mcl-1, reducing colony formation, and inducing apoptosis. Additionally, CDK9-IN-36 exhibits antitumor activity in xenograft models.

Research Area

Cell Biology

Images & Validation

Key Properties

MW565.61
FormulaC30H33F2N5O4
TargetApoptosis,CDK

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

CDK9-IN-36 (orb2944572)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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