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| Catalog Number | orb2944572 |
|---|---|
| Category | Small Molecules |
| Description | CDK9-IN-36 (Compound T7) is a potent, selective, and metabolically stable CDK9 inhibitor with an IC50 value of 1.2 nM. It effectively suppresses the proliferation of Osimertinib-resistant NSCLC cells by downregulating Mcl-1, reducing colony formation, and inducing apoptosis. Additionally, CDK9-IN-36 exhibits antitumor activity in xenograft models. |
| Target | Apoptosis,CDK |
| MW | 565.61 |
| Formula | C30H33F2N5O4 |
| Storage | -20°C |
| Research Area | Cell Biology |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)