CDK9-IN-35

SKU: orb2695372

Description

CDK9-IN-35 (compound 10j) is a potent and selective CDK9/Cyclin T1 kinase inhibitor with an IC50 of 10.2 nM. It demonstrates anti-proliferative activity in the HCT-116 colorectal cancer cell line (IC50 = 20 nM), making it a useful chemical probe for studying transcriptional regulation in oncology research.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• MW: 543.01
• Formula: C₂₆H₂₄ClFN₄O₄S
• SMILES: O=C(C=C)NCC1=NN(C=C1)CC=2C=C3ON=C(NS(=O)(=O)CC4CCCCC4)C3=C(OC)C2
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

169079102