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CDK9-IN-19

SKU: orb1686552

Description

CDK9-IN-19 is a potent and selective CDK9 inhibitor (IC50 = 2.0 nM) with anti-proliferative activity in cancer cells. It demonstrates efficacy in MV4-11 xenograft models and is a research tool for studying acute myeloid leukemia (AML), offering moderate PK properties and low hERG liability.

Research Area

Cell Biology, Epigenetics & Chromatin

Images & Validation

Key Properties

CAS Number2479306-60-8
MW508.47
FormulaC26H22F2N4O5
SMILESC(C)(=O)C1=C(C=2C(=CC(NC=3N=C(C(F)=CN3)C4=C(OC)C=C(F)C=C4)=CC2)OC1=O)N5CCOCC5
TargetCDK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information