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CDK9 Antagonist-1

SKU: orb1985021

Description

CDK9 Antagonist-1 (compounds 11c) is a potent and selective PROTAC-based CDK9 degrader, demonstrating an IC50 of 17 μM in MCF-7 breast cancer cells. This compound, which utilizes a wogonin-derived linker to engage the CRBN E3 ligase, is a valuable chemical probe for investigating CDK9-dependent transcription in oncology and molecular pharmacology research.

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TargetOthers

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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CDK9 Antagonist-1 (orb1985021)

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