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CDK6-IN-2

SKU: orb3210380

Description

CDK6-IN-2 is a covalent inhibitor of CDK6, with an IC50 of 0.013 μM. It can inhibit proliferation and migration of triple-negative breast cancer cells, inducing cell cycle arrest and apoptosis (apoptosis). Additionally, CDK6-IN-2 promotes ROS accumulation and mitochondrial damage through cellular metabolic reprogramming. This compound exhibits antitumor activity and is applicable in the research of triple-negative breast cancer.

Images & Validation

Key Properties

TargetApoptosis,Caspase,Autophagy,CDK,ROS

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information