CDK4/6-IN-8

SKU: orb1688146

Description

CDK4/6-IN-8 (Compound 7p) is a potent and selective dual inhibitor of CDK4 (IC50=5.01 nM) and CDK6 (IC50=3.97 nM). This small molecule is a valuable research tool for studying cell cycle dysregulation and is frequently utilized in both in vitro and in vivo cancer research, particularly in oncology models related to cyclin D-CDK4/6 pathway activation.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2649120-22-7
• MW: 398.37
• Formula: C₁₈H₁₈N₆O₅
• SMILES: C(NC=1C=CC=NC1)(=O)[C@@H]2N(C(NNC(=O)C3=CC=C(N(=O)=O)C=C3)=O)CCC2
• Target: Others,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156768196