CDK4/6-IN-5

SKU: orb1690938

Description

CDK4/6-IN-5 is a potent and selective small molecule inhibitor of CDK4 and CDK6 kinases, exhibiting Ki values of 0.2 nM and 4.4 nM, respectively. This compound is a valuable research tool for studying cell cycle progression and has been utilized in both in vitro and in vivo models of cancer research.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2380321-50-4
• MW: 527.01
• Formula: C₂₂H₂₈ClFN₆O₄S
• SMILES: C[C@@H](O)c1nc2c(F)cc(cc2n1C(C)C)-c1nc(N[C@@H]2CCN(C[C@H]2O)S(C)(=O)=O)ncc1Cl
• Target: Others,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146219888