CDK4/6-IN-20

SKU: orb2564574

Description

CDK4/6-IN-20 (Compound II-5) is a potent and selective CDK4/6 inhibitor with IC50 values of 1.9 nM and 14.2 nM, respectively. It effectively inhibits cell proliferation and is a valuable chemical tool for cancer research, including studies on cell cycle arrest in vitro.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3033950-84-1
• MW: 421.47
• Formula: C₂₃H₂₄FN₅O₂
• SMILES: CC=1C2(C=3C(N1)=C(F)C=C(C3)C=4C(C#N)=CN=C(N[C@H]5[C@H](O)COCC5)N4)CCCC2
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171487580