CDK4/6-IN-17

SKU: orb2278189

Description

CDK4/6-IN-17 is a potent and orally bioavailable small molecule inhibitor of CDK4/6 kinases. It exhibits in vitro anti-proliferative activity in BE(2) cells and has demonstrated significant in vivo efficacy by inhibiting tumor growth in a COLO205 xenograft model, supporting its use in cancer research.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2035069-96-4
• MW: 540.56
• Formula: C₂₇H₂₈F₄N₈
• SMILES: C(F)(F)[C@H]1N2C=3C(N=C2CC1)=C(F)C=C(C3)C4=NC(NC5=CC=C(CN6CCN(CC)CC6)C=N5)=NC=C4F
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

122657619