CDK4/6-IN-15

SKU: orb1744561

Description

CDK4/6-IN-15 is an orally bioavailable, selective CDK4/6 inhibitor that induces G1 cell cycle arrest. It functions by inhibiting Rb phosphorylation at S780 and downregulating E2F-driven gene expression, making it a valuable tool for studying cell cycle dynamics in cancer research, both in vitro and in vivo.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2078047-99-9
• MW: 442.56
• Formula: C₂₁H₂₇FN₈S
• SMILES: CC1=C(SC(NC)=N1)C2=NC(NC3=CC=C(C=N3)N4CCC(N(C)C)CC4)=NC=C2F
• Target: Others,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135286280