CDK2/9-IN-1

SKU: orb2945921

Description

CDK2/9-IN-1 (compound 20a) is a potent, orally bioavailable dual inhibitor of CDK2 (IC50=4 nM) and CDK9 (IC50=9 nM). It demonstrates antitumor activity by inducing G2/M phase arrest and apoptosis in cancer cells, making it a valuable chemical probe for oncology research in both cellular and animal models.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 2222285-23-4
• MW: 362.43
• Formula: C₁₄H₁₄N₆O₂S₂
• SMILES: O=S(=O)(N)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=NC=CS3)C
• Target: Apoptosis,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677368