CDK2-IN-45

SKU: orb3028038

Description

CDK2-IN-45 is a CDK2 inhibitor with an IC50 value of 0.64 μM. It effectively inhibits the proliferation of DU-145 and PC-3 cell lines, with IC50 values of 2.20 μM and 4.17 μM, respectively. Additionally, CDK2-IN-45 induces G0/G1 phase cell cycle arrest and apoptosis. It is utilized in prostate cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• MW: 453.95
• Formula: C₂₅H₁₆ClN₅S
• SMILES: ClC(C=C1)=CC=C1C2=CC=NC3=C(C(NC4=CC=CC=C4)=NN32)C5=NC6=CC=CC=C6S5
• Target: Apoptosis,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,CDK