CDK2-IN-18

SKU: orb2566656

Description

CDK2-IN-18 (compound 8q) is a potent dual inhibitor of CDK2/E and CDK4/D1 with IC50 values of 8 nM and 46 nM, respectively. It demonstrates robust anti-proliferative activity in tumor cell assays, making it a valuable chemical probe for cancer research in both in vitro and in vivo studies.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 364735-73-9
• MW: 437.52
• Formula: C₂₁H₂₃N₇O₂S
• SMILES: O=C1C=2C(C=3C1=C(NC(NN4CCN(C)CC4)=O)C=CC3)=NNC2C=5SC(C)=NC5C
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5288018