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CDK ligand for PROTAC

SKU: orb1992918

Description

This small molecule serves as a CDK-inhibiting ligand for constructing PROTAC degraders targeting CDK4/6. It enables the development of bifunctional molecules for probing cyclin-dependent kinase function and degradation in cancer research, with utility in both cellular and in vivo models for studying oncogenic pathways.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW494.54
FormulaC25H28F2N8O
SMILESFC(C=N1)=C(C2=CC(N(C(C)C)C(CO)=N3)=C3C(F)=C2)N=C1NC4=NC=C(C=C4)CN5CCNCC5
TargetOthers,Ligands for Target Protein for PROTAC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

CDK ligand for PROTAC (orb1992918)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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