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CDK ligand for PROTAC hydrochloride

SKU: orb1710112

Description

This small molecule serves as a CDK-inhibiting ligand for constructing PROTAC degraders targeting CDK4/6. It exhibits antitumor activity and is utilized in cancer research for studying targeted protein degradation both in vitro and in vivo.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW531
FormulaC25H29ClF2N8O
SMILESFC(C=N1)=C(C2=CC(N(C(C)C)C(CO)=N3)=C3C(F)=C2)N=C1NC4=NC=C(C=C4)CN5CCNCC5.[H]Cl
TargetOthers,Ligands for Target Protein for PROTAC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

CDK ligand for PROTAC hydrochloride (orb1710112)

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Available Sizes

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200 mg
500 mg
5 mg
$ 360.00
1 ml x 10 mM (in DMSO)
$ 410.00
10 mg
$ 530.00
25 mg
$ 920.00
50 mg
$ 1,500.00
100 mg
$ 2,030.00