CDD-1431

SKU: orb2945012

Description

CDD-1431 is a potent and selective BMPR2 kinase inhibitor (Kiapp = 20.6 nM) that blocks BMP signaling, as shown by its inhibition of a BRE-luciferase reporter (IC50 = 4.87 µM). This tool compound is useful for studying BMP pathway roles in renal, musculoskeletal, cardiac, and reproductive biology, as well as heterotopic ossification, in both cellular and animal models.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3034216-31-1
• MW: 658.77
• Formula: C₃₃H₃₈N₈O₅S
• SMILES: O=C(NCC=1C=CC=C(C1)N2CCN(C3=NC(=NC=C3OC)NC4=CC=CC(=C4)S(=O)(=O)N)CC2)C5=CC=C(C=C5)CCC(=O)NC
• Target: TGF-beta/Smad

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171849409