Cdc7-IN-18

SKU: orb1688599

Description

Cdc7-IN-18 is a potent and selective CDC7/DBF4 kinase inhibitor with an IC50 of 1.29 nM. It demonstrates robust antiproliferative activity in COLO205 cells (IC50 = 53.62 nM), making it a valuable chemical probe for researching DNA replication and cell cycle mechanisms in cancer models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2562329-14-8
• MW: 367.47
• Formula: C₁₉H₂₁N₅OS
• SMILES: O=C1C2=C(C3=C(S2)C=4C(CCC3)=NNC4)NC(=N1)[C@@H]5N6CCC(C5)CC6
• Target: CDK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155354036