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Catalog Number | orb749365 |
---|---|
Category | Antibodies |
Description | CD11c, also known as Integrin alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | HC1/1 |
Tested applications | FACS, Functional Studies, IF |
Reactivity | Human |
Isotype | Mouse IgG1, kappa |
Immunogen | Human monocytic U937 phorbol ester-treated cells were used as the immunogen for this CD11c antibody. |
Dilution range | Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 0.5-1ug/ml,Functional studies (order BSA/sodium azide-free format) |
Purity | Protein G affinity chromatography |
Conjugation | Unconjugated |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
Hazard Information | This CD11c antibody is available for research use only. |
Entrez | 3687 |
Storage | Store the CD1°C antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide). |
Buffer/Preservatives | 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide |
Note | For research use only |
Application notes | The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11c antibody to be titered up or down for optimal performance. |
Expiration Date | 12 months from date of receipt. |
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