CD 10899

SKU: orb2566659

Description

CD 10899 is a hydroxylated metabolite of Volasertib and a potent, ATP-competitive inhibitor of Polo-like kinase 1 (PLK1) with an IC50 of 6 nM. This active metabolite is utilized in cancer research for investigating PLK1 signaling in both in vitro and in vivo experimental models.

Research Area

Cell Biology

Key Properties

• CAS Number: 1331770-20-7
• MW: 634.81
• Formula: C₃₄H₅₀N₈O₄
• SMILES: C(C)(C)N1C=2C(N(C)C(=O)C1(CC)O)=CN=C(NC3=C(OC)C=C(C(N[C@H]4CC[C@@H](CC4)N5CCN(CC6CC6)CC5)=O)C=C3)N2
• Target: PLK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

53354750