CCT244747

SKU: orb1707485

Description

CCT244747 is an orally bioavailable, ATP-competitive, and highly selective CHK1 inhibitor. It demonstrates cytotoxic activity by overriding DNA damage-induced S and G2 cell cycle arrest and promoting apoptosis in various tumor cell lines in vitro. Its research applications include investigating checkpoint signaling and combination therapies in oncology models.

Research Area

Cell Biology

Key Properties

• CAS Number: 1404095-34-6
• MW: 408.46
• Formula: C₂₀H₂₄N₈O₂
• SMILES: COc1cc(Nc2cnc(C#N)c(O[C@H](C)CN(C)C)n2)ncc1-c1cnn(C)c1
• Target: Chk

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

54758482